Endocrine Abstracts

We present a case of a 52 year old man with a past medical history of primary hypothyroidism on treatment, presenting with elevated TSH levels, suggesting inadequate thyroxine replacement. The patient was managed with 200 mcg of thyroxine for 14 years with no compliance issues. TSH levels failed to normalise despite increasing the dose of thyroxine. In addition to elevated TSH levels the patient noted progressive leg swelling and associated shortness of breath over the precedi...

This is a case of a 49 year old obese Caucasian female who was referred to an endocrinology clinic for investigation of Cushing’s syndrome, based on raised blood pressure and cushingnoid facies. The patient had underlying schizophrenia and was stable on clozapine. Her blood pressure was 150/99 mmHg on bendrofluoriomethiazide and candesartan. Her 24 hour urinary free cortisol was normal but 24 hour urinary free noradrenaline was elevated at 835 nmol (76–561) with norm...